Latest HAL publications
- [hal-04093583] Nanomedicine-based potential phyto-drug delivery systems for diabetesby ano.nymous@ccsd.cnrs.fr.invalid (Badr Bahloul) on 31 March 2025
Diabetes is one of the 21st-century major health concerns, considered the sixth leading cause of death, and expected to rise to more than 642 million people by 2040. Three types of diabetes exist, differing in their etiology: Type 1 (T1DM) and 2 […]
- [tel-04873486] Fingerprint approach using macrocyclic chemical nose sensors for disease diagnosticsby ano.nymous@ccsd.cnrs.fr.invalid (Monica Swetha Bosco) on 21 March 2025
Sensors play a crucial role in our daily lives, continuously monitoring and regulating our health, environment and safety. Nature has been a significant inspiration for the creation of artificial sensing systems. A prototypical and remarkable […]
- [hal-04954331] Clinical, biological, metabolic and immune changes associated with the use of Sodium-glucose cotransporter 2...by ano.nymous@ccsd.cnrs.fr.invalid (Vincent Guiraud) on 18 February 2025
Introduction : Positive cardiovascular and renal outcomes associated with the Sodium-Glucose cotransporter 2 inhibitor (SGLT2i) use are attributed to their anti-inflammatory properties. Persistent immune activation accounts for part of people living […]
- [hal-04945679] Binary phase diagrams between ascorbic acid and PEG 1500, 4000 and 6000by ano.nymous@ccsd.cnrs.fr.invalid (Elena Losi) on 13 February 2025
Solid dispersions of ascorbic acid in 3 different PEG matrices, PEG 1500, 4000 and 6000 were studied by thermal analyzes and X-ray diffraction. Vitamin C was mixed in different mass proportions with each of the PEGs, thus making it possible to […]
- [tel-04938353] Elaboration of pharmaceutical interest nanosized crystals for bioavailability improvement of drugsby ano.nymous@ccsd.cnrs.fr.invalid (Panpan Ma) on 10 February 2025
In this study, nanocrystalline suspensions (NCs) of Fisetin and Curcumin and a combination of etoposide (ETO) and prednisolone (PRD) were developed for potential applications in nanomedicine. The NCs demonstrated excellent characteristics, including […]
- [hal-04934942] Sialyl Lewis X (sLex):Biological functions, synthetic methods and therapeutic implicationsby ano.nymous@ccsd.cnrs.fr.invalid (Leyu Tang) on 7 February 2025
Carbohydrates are shown to be crucial to several biological processes. They are essential mediators of cell-cell recognition processes. Among them, Sialyl Lewis X (sLe x ) is a very significant structure in the human body. It is a critical […]
- [hal-04888066] Correcting Autoinflammation in STING-Associated Vasculopathy with Onset in Infancy (SAVI) by Human Stem Cell...by ano.nymous@ccsd.cnrs.fr.invalid (Sebastien Viel) on 15 January 2025
Abstract Type I interferonopathies comprise a large group of Mendelian autoinflammatory diseases that generally lack effective treatments. STING-associated Vasculitis with onset in Infancy (SAVI) is a severe autosomal dominant disease due to […]
- [hal-04873453] Bimodal Array-Based Fluorescence Sensor and Microfluidic Technology for Protein Fingerprinting and Clinical...by ano.nymous@ccsd.cnrs.fr.invalid (Monica Swetha Bosco) on 8 January 2025
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- [hal-04837139] Design of new nano-tools to target mitochondria and study the metabolic plasticity of cancer cellsby ano.nymous@ccsd.cnrs.fr.invalid (Dorna Akbarzadeh) on 17 December 2024
Metabolic plasticity and mitochondrial function are crucial in tumorigenesis and cancer therapy response, making mitochondria a key target for novel treatments (1-2). Bioactive molecules, modulating mitochondrial activity, offer alternative […]
- [hal-04831942] MULTIFUNCTIONAL NANOPARTICLES TO FIGHT HORMONE-RESISTANT PROSTATE CANCERby ano.nymous@ccsd.cnrs.fr.invalid (Killian Laguerre) on 11 December 2024
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- [hal-04790449] NANOPARTICLE FOR THE DETECTION OF H 20 2by ano.nymous@ccsd.cnrs.fr.invalid (Cyrille Richard) on 19 November 2024
<div xmlns="http://www.tei-c.org/ns/1.0"><head>Field of the invention</head><p>The present invention relates to a method for the detection of H2O2 in a sample comprising a persistent luminescence […]
- [hal-04790380] Improvement of Hydrogen Peroxide and Glucose Detection in Serum using Persistent Luminescent Nanoparticles: Impact...by ano.nymous@ccsd.cnrs.fr.invalid (Zied Ferjaoui) on 19 November 2024
Persistent Luminescent Nanoparticles (PLNPs) emit prolonged light after excitation, allowing getting images with high signal‐to‐noise ratio, making them particularly beneficial for in vitro biodetection. In this study, we report the […]