Latest HAL publications

<div xmlns="http://www.tei-c.org/ns/1.0"><p>The rapid advancement of nanomedicines is heralding promising opportunities for enhancing treatment efficacy and minimizing adverse effects. Notably, nanomedicines offer the potential to […]

Monoclonal antibodies (mAbs) therapeutics cannot evade the occurrence of adverse effects. Thus, mAbs are commonly triggering immune responses corresponding to the expression of anti-drug antibodies. Anti-drug antibodies can neutralize mAbs, leading […]

La fibrose hépatique est une conséquence majeure des pathologies chroniques du foie telles que la stéatohépatite métabolique (MASH). La fibrose à un stade très avancé devient une cirrhose et peut dégénérer en carcinome hépatocellulaire. […]

Erythropoietin (EPO) is a hormone primarily produced by the kidneys that stimulates the production of red blood cells. Its systemic concentration increases in response to anemia or hypoxia. In addition to this increase in endogenous production, […]

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Background and Objectives Anti-NMDAR encephalitis (NMDARE) is a severe neurologic condition, and recently, the NMDAR Encephalitis One-Year Functional Status (NEOS) score has emerged as a 1-year prognostic tool. This study aimed to evaluate NEOS […]

Diabetes is one of the 21st-century major health concerns, considered the sixth leading cause of death, and expected to rise to more than 642 million people by 2040. Three types of diabetes exist, differing in their etiology: Type 1 (T1DM) and 2 […]

Sensors play a crucial role in our daily lives, continuously monitoring and regulating our health, environment and safety. Nature has been a significant inspiration for the creation of artificial sensing systems. A prototypical and remarkable […]

Introduction : Positive cardiovascular and renal outcomes associated with the Sodium-Glucose cotransporter 2 inhibitor (SGLT2i) use are attributed to their anti-inflammatory properties. Persistent immune activation accounts for part of people living […]

Solid dispersions of ascorbic acid in 3 different PEG matrices, PEG 1500, 4000 and 6000 were studied by thermal analyzes and X-ray diffraction. Vitamin C was mixed in different mass proportions with each of the PEGs, thus making it possible to […]

In this study, nanocrystalline suspensions (NCs) of Fisetin and Curcumin and a combination of etoposide (ETO) and prednisolone (PRD) were developed for potential applications in nanomedicine. The NCs demonstrated excellent characteristics, including […]

Carbohydrates are shown to be crucial to several biological processes. They are essential mediators of cell-cell recognition processes. Among them, Sialyl Lewis X (sLe x ) is a very significant structure in the human body. It is a critical […]