Latest HAL publications
- [hal-04790449] NANOPARTICLE FOR THE DETECTION OF H 20 2by ano.nymous@ccsd.cnrs.fr.invalid (Cyrille Richard) on 19 November 2024
<div xmlns="http://www.tei-c.org/ns/1.0"><head>Field of the invention</head><p>The present invention relates to a method for the detection of H2O2 in a sample comprising a persistent luminescence […]
- [hal-04790380] Improvement of Hydrogen Peroxide and Glucose Detection in Serum using Persistent Luminescent Nanoparticles: Impact...by ano.nymous@ccsd.cnrs.fr.invalid (Zied Ferjaoui) on 19 November 2024
Persistent Luminescent Nanoparticles (PLNPs) emit prolonged light after excitation, allowing getting images with high signal‐to‐noise ratio, making them particularly beneficial for in vitro biodetection. In this study, we report the […]
- [hal-04758748] Combination of designed liposomes and sonoporation provide drug release or immunomodulationby ano.nymous@ccsd.cnrs.fr.invalid (Bich-Thuy Doan) on 29 October 2024
Liposomes are extremely interesting to overcome some limitations of drugs, such as cytotoxicity, however, sometimes, liposomes are not sufficient by themselves to overcome the complexity of the environment, in particular in cancer, where the […]
- [hal-04758692] Nanocrystals as novel nanomedicines in cancerby ano.nymous@ccsd.cnrs.fr.invalid (Nathalie Mignet) on 29 October 2024
Nanomedicine represents alternative solutions to treat patients with cancer limiting toxicity to certain organs related to large systemic amount of drug and providing better accumulation in vascularized tumors. Despite the encapsulation of drugs […]
- [hal-04758657] Prague Meeting on Tumor Therapy and Imaging 2023by ano.nymous@ccsd.cnrs.fr.invalid (Johanne Seguin) on 29 October 2024
Albumin is a common endogenous protein which is relatively easy to chemically modify. In the past, we were interested in targeting asialoglycoprotein receptors to evaluate the liver function. Using SPECT1 and optical imaging2, we observed a fast […]
- [hal-04758629] Combination of Tumor Thermal Ablation, Cytokines and Lipidic Adjuvant Provide a Distal Immune Responseby ano.nymous@ccsd.cnrs.fr.invalid (Nathalie Mignet) on 29 October 2024
Context Cancer immunotherapy in combination with nanomedicine is of high interest to achieve a systemic immune response. Additional physical methods can bring the specificity related to immunogenic cell death. In the literature, interleukin-12 […]
- [hal-04724534] Constitutional DNA Polymorphisms Associated with the Plasma Imatinib Concentration in Chronic Myeloid Leukemia...by ano.nymous@ccsd.cnrs.fr.invalid (Heriberto Bruzzoni-Giovanelli) on 24 October 2024
The tyrosine kinase Inhibitor (TKI) imatinib is approved for the treatment of the chronic phase of chronic myeloid leukemia (CP-CML). Pharmacokinetic studies have highlighted the importance of inter-patient variability on imatinib plasma trough […]
- [hal-04746208] Chromium-doped zinc gallate: Impact of Sn4+ co-doping on the persistent luminescence properties at the nanoscale...by ano.nymous@ccsd.cnrs.fr.invalid (Guanyu Cai) on 21 October 2024
<div><p>Persistent luminescence (PersL) nanoparticles emit a signal that lasts long after the excitation has ended, enabling highly sensitive bioimaging without background noise. When using UV light as excitation source before the […]
- [hal-04740800] A translational study for biomarker identification of PEP-010, a pro-apoptotic peptide restoring apoptosis in...by ano.nymous@ccsd.cnrs.fr.invalid (D. Germini) on 17 October 2024
<div><p>PEP-010 is a pro-apoptotic peptide based on a proprietary cell-penetrating and interfering peptide technology for the treatment of advanced solid tumors.</p><p>• PEP-010 acts by disrupting the interaction between […]
- [hal-04734518] La phospholipase A2 associée aux lipoprotéines (Lp-PLA2) : biomarqueur pertinent et cible thérapeutique ?by ano.nymous@ccsd.cnrs.fr.invalid (Dominique Bonnefont-Rousselot) on 14 October 2024
<div><p>Depuis une quinzaine d'années, de nombreuses études cherchent à identifier le rôle de la phospholipase A2 associée aux lipoprotéines (Lp-PLA2) dans les pathologies ayant une composante d'inflammation vasculaire, parmi […]
- [hal-04453293] Effect of Molecules’ Physicochemical Properties on Whey Protein/Alginate Hydrogel Rheology, Microstructure and...by ano.nymous@ccsd.cnrs.fr.invalid (A. Delanne-Cuménal) on 9 October 2024
The encapsulation of molecules with different physicochemical properties (theophylline, blue dextran, salicylic acid and insulin) in whey protein (WP) and alginate (ALG) microparticles (MP) for oral administration was studied. MP based on WP/ALG […]
- [hal-04626840] Radiofrequency Combined with Intratumoral Immunotherapy: Preclinical Results and Safety in Metastatic Colorectal...by ano.nymous@ccsd.cnrs.fr.invalid (Johanne Seguin) on 17 July 2024
Radiofrequency ablation (RFA) of cancer induces an anti-tumor immunity, which is insufficient to prevent recurrences. In mice, RFAu2013intratumoral immunotherapy by granulocyteu2013macrophage colony-stimulating factor (GM-CSF) and Bacillus […]