Publications de l’équipe Biothérapie

Retour équipe biothérapie

Articles scientifiques [2025]

 

Purification protocol of hypertrophied hepatic stellate cells for their transcriptomic characterization from CDAHFD mice liver

Heckmann M, Djerir NEH, Commere PH, Fernandes J, Sarrabayrouse G, Bigey P, Escriou V, Hoffmann C

bioRxiv: 2025.05.19.654829 > doi: 10.1101/2025.05.19.654829

 

A translational study for biomarker identification of PEP-010, a pro-apoptotic peptide restoring apoptosis in cancer models

Germini D, Farhat R, Dadon L, Lacroix A, Nemati F, Rebollo A, Decaudin D, Wiels J, Brenner C.

Biochim Biophys Acta Mol Basis Dis, 2025, 1871(1):167492  > doi:10.1016/j.bbadis.2024.167492

 

Exploring the interaction between a LRRK2/PP1CA interfering peptide and PP1CA

Dominguez-Meijde J, Murail S, Boudjelloul R, Rebollo A, Tuffery P.

J Mol Graph Model, 2025, 141: 109140 >doi: 10.1016/j.jmgm.2025.109140

 

Antitumoral Effect on Liver Cancer of a Tumor-Penetrating and Interfering Peptide

Savier E, Tuffery P, Bruzoni-Giovannelli H, Boudjelloul R, Rebollo A.

2025, In: Langel, Ü. (eds) Cancer-Targeted Drug Delivery. Methods in Pharmacology and Toxicology. Humana, New York, NY  > doi: 10.1007/978-1-0716-4374-7_2

 

Articles scientifiques [2024]

 

Intracellular delivery of functional proteins with DNA protein nanogels-lipids complex

Mariconti M, Dechamboux L, Heckmann M, Gros J, Morel M, Escriou V, Baigl D, Hoffmann C, Rudiuk S.

J Am Chem Soc, 2024, 146(8):5118-5127 > doi: 10.1021/jacs.3c08000

 

Constitutional DNA polymorphisms associated with the plasma Imatinib concentration in Chronic Myeloid Leukemia patients

Bruzzoni-Giovanelli H, Zouali H, Sahbatou M, Maneglier B, Cayuela M, Rebollo A, Marin G, Geromin D, Tomczak C, Alberdi A, Jean-Francois Deleuze JF, Rousselot P.

Pharmaceutics, 2024, 16 :834 > doi: 10.3390/pharmaceutics16060834

 

Alternative routes for parenteral nucleic acid delivery and related hurdles: highlights in RNA delivery Cunha J, Ventura FV, Charrueau C, Ribeiro AJ.

Expert Opin Drug Deliv, 2024, 21(10):1415-1439 > doi: 10.1080/17425247.2024.2405207

 

Articles scientifiques [2023]

 

The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits

Tonello R, Anderson WB, Davidson S, Escriou V, Yang L, Schmidt BL, Imlach WL, Bunnett NW

Pain, 2023, 164:1355-1374 > doi: 10.1097/j.pain.0000000000002826

 

In silico and in vivo studies of a tumor penetrating and interfering peptide with antitumoral effect on xenograft models of breast cancer.

Marin G, Murail S, Andrini L, Garcia M, Loisel S, Tuffery P and Rebollo A.

Pharmaceutics, 2023, 15:1180 > doi: 10.3390/pharmaceutics15041180

 

Differencial expression of PP2A and Set in hepatocellular carcinoma : antitumoral effect of an interfering peptide blocking the interaction.

Boudjelloul R, Rebollo A, Loisel S, Charlotte F, Franetich JF, Savier E.

Clin Oncol, 2023, 8(1):2028.

 

Development and Application of an Assay to Evaluate the Anti-Parasitic Effect of Humoral Responses against Trypanosoma cruzi.

Martinez-Peinado N, Gabaldon-Figueira JC, Martinez-Añon I, Rodríguez-Gordo C, Robleda-Castillo R, Pinazo MJ, Bigey P, Gascon J, Alonso-Padilla J.

Microorganisms, 2023, 11(2):241 > doi: 10.3390/microorganisms11020241

 

Integrated omics approach for the identification of HDL structure-function relationships in PCSK9-related familial hypercholesterolemia.

Darabi M, Lhomme M, Ponnaiah M, Pučić-Baković M, Guillas I, Frisdal E, Bittar R, Croyal M, Matheron-Duriez L, Poupel L, Bonnefont-Rousselot D, Frere C, Varret M, Krempf M, Cariou B, Lauc G, Guerin M, Carrie A, Bruckert E, Giral P, Le Goff W, Kontush A.

J Clin Lipidol, 2023, 17(5):643-658 > DOI: 10.1016/j.jacl.2023.07.003

 

In Silico and In Vivo Studies of a Tumor-Penetrating and Interfering Peptide with Antitumoral Effect on Xenograft Models of Breast Cancer.

Marin GH, Murail S, Andrini L, Garcia M, Loisel S, Tuffery P, Rebollo A.

Pharmaceutics, 2023, 15(4):1180 > doi: 10.3390/pharmaceutics15041180

 

Traitement topique de la dégénérescence maculaire liée à l’âge. Où en sommes-nous ?

Pierre M, Lamaa D, Fabre M, Ronco C, Benhida R, Demange L, Charrueau C.

Med Sci, 2023, 39(12):958-966 > doi: 10.1051/medsci/2023177

Articles scientifiques [2022]

 

Isolation of Primary Hepatocytes for Testing Tumor Penetrating Peptides

Savier E, Tuffery P, Bruzzoni-Giovanelli H, Rebollo A

Methods Mol Biol, 2022, 2383: 413-427 > doi: 10.1007/978-1-0716-1752-6_26

 

Molecular mechanisms in Alzheimer’s disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules

Oumata N, Lu K, Teng Y, Cavé C, Peng Y, Galons H, Roques BP

Eur J Med Chem, 2022, 240: 114578 > doi: 10.1016/j.ejmech.2022.114578

 

Binding and Kinetic Analysis of Human Protein Phosphatase PP2A Interactions with Caspase 9 Protein and the Interfering Peptide C9h

Dorgham K, Murail S, Tuffery P, Savier E, Bravo J, Rebollo A

Pharmaceutics, 2022, 14: 2055 > doi: 10.3390/pharmaceutics14102055

 

Burden of liver disease progression of patients with type-2 diabetes: a retrospective longitudinal cohort study

Mallet V, Parlati L, Martinino A, Scarano Pereira JP, Navas Jimenez C, Sakka M, Bouam S, Retbi A, Meritet J-F, Thabut D, Rufat P, Bonnefont-Rousselot D, Sogni P, Pol S, Tsochatzis E, for the Demosthenes research group.

J Hepatol, 2022, 76: 265-274 > doi: 10.1016/j.jhep.2021.09.030

 

Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response

Do HD, Marie C, Bessoles S, Dhotel H, Seguin J, Larrat B, Doan BT, Scherman D, Escriou V, Hacein-Bey-Abina S, Mignet N

Explor Target Antitumor Ther, 2022, 3: 398-413 > doi: 10.37349/etat.2022.00090

 

Preclinical Validation of Tumor-Penetrating and Interfering Peptides against Chronic Lymphocytic Leukemia

Simón-Gracia L, Loisel S, Sidorenko V, Scodeller P, Parizot C, Savier E, Haute T, Teesalu T, Rebollo A

Mol Pharm, 2022, 19 : 895-903 > doi: 10.1021/acs.molpharmaceut.1c00837

 

Extracellular vesicle-mediated metastasis suppressors NME1 and NME2 modify lipid metabolism in fibroblasts

Matyasi B, Petovari G, Danko T, Butz H, Liko I, Low P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnar K, Paloczi K, Buzas EI, Boissan M, Sebestyen A, Takacs-Vellai K

Cancers, 2022, 14: 3913 > doi: 10.3390/cancers14163913

 

Computer-Aided Analysis of West Sub-Saharan Africa Snakes Venom towards the Design of Epitope-Based Poly-Specific Antivenoms

Ros-Lucas A, Bigey P, Chippaux JP, Gascón J, Alonso-Padilla J

Toxins (Basel), 2022, 14: 418 > doi: 10.3390/toxins14060418

 

PEPscan: A Broad Spectrum Approach for the Characterization of Protein-Binder Interactions?

Rebollo A, Fliedel L, Tuffery P

Biomolecules, 2022, 12: 178 > doi: 10.3390/biom12020178

 

Spheroplexes: Hybrid PLGA-cationic lipid nanoparticles, for in vitro and oral delivery of siRNA

Arruda DC, Lachagès AM, Demory H, Escriou G, Lai-Kuen R, Dugas PY, Hoffmann C, Bessoles S, Sarrabayrouse G, Malachias A, Finet S, Gastelois PL, de Almeida Macedo WA, da Silva Cunha A Jr, Bigey P, Escriou V

J Control Release, 2022, 350: 228-243 > doi: 10.1016/j.jconrel.2022.08.030

Retour équipe biothérapie